leiden clustering explained

First calculate k-nearest neighbors and construct the SNN graph. Hence, by counting the number of communities that have been split up, we obtained a lower bound on the number of communities that are badly connected. Louvain quickly converges to a partition and is then unable to make further improvements. Introduction leidenalg 0.9.2.dev0+gb530332.d20221214 documentation In the first iteration, Leiden is roughly 220 times faster than Louvain. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior. The corresponding results are presented in the Supplementary Fig. Zenodo, https://doi.org/10.5281/zenodo.1469357 https://github.com/vtraag/leidenalg. Nonlin. The algorithm then locally merges nodes in \({{\mathscr{P}}}_{{\rm{refined}}}\): nodes that are on their own in a community in \({{\mathscr{P}}}_{{\rm{refined}}}\) can be merged with a different community. One may expect that other nodes in the old community will then also be moved to other communities. Class wrapper based on scanpy to use the Leiden algorithm to directly cluster your data matrix with a scikit-learn flavor. The numerical details of the example can be found in SectionB of the Supplementary Information. Hence, the problem of Louvain outlined above is independent from the issue of the resolution limit. Figure4 shows how well it does compared to the Louvain algorithm. GitHub - MiqG/leiden_clustering: Cluster your data matrix with the The Leiden algorithm consists of three phases: (1) local moving of nodes, (2) refinement of the partition and (3) aggregation of the network based on the refined partition, using the non-refined partition to create an initial partition for the aggregate network. Modules smaller than the minimum size may not be resolved through modularity optimization, even in the extreme case where they are only connected to the rest of the network through a single edge. Note that communities found by the Leiden algorithm are guaranteed to be connected. The nodes are added to the queue in a random order. Source Code (2018). This phenomenon can be explained by the documented tendency KMeans has to identify equal-sized , combined with the significant class imbalance associated with the datasets having more than 8 clusters (Table 1). Second, to study the scaling of the Louvain and the Leiden algorithm, we use benchmark networks, allowing us to compare the algorithms in terms of both computational time and quality of the partitions. ML | Hierarchical clustering (Agglomerative and Divisive clustering Phys. To obtain Leiden is both faster than Louvain and finds better partitions. Leiden is faster than Louvain especially for larger networks. In this iterative scheme, Louvain provides two guarantees: (1) no communities can be merged and (2) no nodes can be moved. MATH In later stages, most neighbors will belong to the same community, and its very likely that the best move for the node is to the community that most of its neighbors already belong to. However, so far this problem has never been studied for the Louvain algorithm. Waltman, Ludo, and Nees Jan van Eck. This enables us to find cases where its beneficial to split a community. For lower values of , the correct partition is easy to find and Leiden is only about twice as fast as Louvain. Figure3 provides an illustration of the algorithm. Lancichinetti, A. They identified an inefficiency in the Louvain algorithm: computes modularity gain for all neighbouring nodes per loop in local moving phase, even though many of these nodes will not have moved. Leiden now included in python-igraph #1053 - Github Directed Undirected Homogeneous Heterogeneous Weighted 1. We used the CPM quality function. The Louvain algorithm is a simple and popular method for community detection (Blondel, Guillaume, and Lambiotte 2008). Crucially, however, the percentage of badly connected communities decreases with each iteration of the Leiden algorithm. This way of defining the expected number of edges is based on the so-called configuration model. In particular, benchmark networks have a rather simple structure. We prove that the Leiden algorithm yields communities that are guaranteed to be connected. J. The images or other third party material in this article are included in the articles Creative Commons license, unless indicated otherwise in a credit line to the material. CPM does not suffer from this issue13. If we move the node to a different community, we add to the rear of the queue all neighbours of the node that do not belong to the nodes new community and that are not yet in the queue. Modularity is a scale value between 0.5 (non-modular clustering) and 1 (fully modular clustering) that measures the relative density of edges inside communities with respect to edges outside communities. The nodes that are more interconnected have been partitioned into separate clusters. Ozaki, N., Tezuka, H. & Inaba, M. A Simple Acceleration Method for the Louvain Algorithm. The Louvain method for community detection is a popular way to discover communities from single-cell data. For each community in a partition that was uncovered by the Louvain algorithm, we determined whether it is internally connected or not. Subpartition -density is not guaranteed by the Louvain algorithm. Run the code above in your browser using DataCamp Workspace. The refined partition \({{\mathscr{P}}}_{{\rm{refined}}}\) is obtained as follows. In this post Ive mainly focused on the optimisation methods for community detection, rather than the different objective functions that can be used. Louvain method - Wikipedia In contrast, Leiden keeps finding better partitions in each iteration. In an experiment containing a mixture of cell types, each cluster might correspond to a different cell type. 10008, 6, https://doi.org/10.1088/1742-5468/2008/10/P10008 (2008). Node optimality is also guaranteed after a stable iteration of the Louvain algorithm. In the Louvain algorithm, a node may be moved to a different community while it may have acted as a bridge between different components of its old community. At this point, it is guaranteed that each individual node is optimally assigned. It is a directed graph if the adjacency matrix is not symmetric. Importantly, the problem of disconnected communities is not just a theoretical curiosity. ADS Google Scholar. The degree of randomness in the selection of a community is determined by a parameter >0. In addition, a node is merged with a community in \({{\mathscr{P}}}_{{\rm{refined}}}\) only if both are sufficiently well connected to their community in \({\mathscr{P}}\). Louvain community detection algorithm was originally proposed in 2008 as a fast community unfolding method for large networks. E Stat. Louvain pruning is another improvement to Louvain proposed in 2016, and can reduce the computational time by as much as 90% while finding communities that are almost as good as Louvain (Ozaki, Tezuka, and Inaba 2016). ADS This makes sense, because after phase one the total size of the graph should be significantly reduced. Our analysis is based on modularity with resolution parameter =1. * (2018). Hierarchical Clustering: Agglomerative + Divisive Explained | Built In In fact, if we keep iterating the Leiden algorithm, it will converge to a partition without any badly connected communities, as discussed earlier. However, modularity suffers from a difficult problem known as the resolution limit (Fortunato and Barthlemy 2007). We prove that the new algorithm is guaranteed to produce partitions in which all communities are internally connected. A Smart Local Moving Algorithm for Large-Scale Modularity-Based Community Detection. Eur. This is similar to ideas proposed recently as pruning16 and in a slightly different form as prioritisation17. Basically, there are two types of hierarchical cluster analysis strategies - 1. We use six empirical networks in our analysis. This amounts to a clustering problem, where we aim to learn an optimal set of groups (communities) from the observed data. Iterating the Louvain algorithm can therefore be seen as a double-edged sword: it improves the partition in some way, but degrades it in another way. 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A Comparative Analysis of Community Detection Algorithms on Artificial Networks. Finding and Evaluating Community Structure in Networks. Phys. From Louvain to Leiden: guaranteeing well-connected communities, $$ {\mathcal H} =\frac{1}{2m}\,{\sum }_{c}({e}_{c}-{\rm{\gamma }}\frac{{K}_{c}^{2}}{2m}),$$, $$ {\mathcal H} ={\sum }_{c}[{e}_{c}-\gamma (\begin{array}{c}{n}_{c}\\ 2\end{array})],$$, https://doi.org/10.1038/s41598-019-41695-z. Phys. SPATA2 currently offers the functions findSeuratClusters (), findMonocleClusters () and findNearestNeighbourClusters () which are wrapper around widely used clustering algorithms. J. https://doi.org/10.1038/s41598-019-41695-z. In our experimental analysis, we observe that up to 25% of the communities are badly connected and up to 16% are disconnected. Furthermore, by relying on a fast local move approach, the Leiden algorithm runs faster than the Louvain algorithm. 1 I am using the leiden algorithm implementation in iGraph, and noticed that when I repeat clustering using the same resolution parameter, I get different results. Phys. As can be seen in Fig. Note that Leiden clustering directly clusters the neighborhood graph of cells, which we already computed in the previous section. The constant Potts model (CPM), so called due to the use of a constant value in the Potts model, is an alternative objective function for community detection. Correspondence to According to CPM, it is better to split into two communities when the link density between the communities is lower than the constant. Biological sequence clustering is a complicated data clustering problem owing to the high computation costs incurred for pairwise sequence distance calculations through sequence alignments, as well as difficulties in determining parameters for deriving robust clusters. Article Scaling of benchmark results for difficulty of the partition. Communities in \({\mathscr{P}}\) may be split into multiple subcommunities in \({{\mathscr{P}}}_{{\rm{refined}}}\). In the local moving phase, individual nodes are moved to the community that yields the largest increase in the quality function. Lancichinetti, A., Fortunato, S. & Radicchi, F. Benchmark graphs for testing community detection algorithms. 8, 207218, https://doi.org/10.17706/IJCEE.2016.8.3.207-218 (2016). CAS In terms of the percentage of badly connected communities in the first iteration, Leiden performs even worse than Louvain, as can be seen in Fig. Sci Rep 9, 5233 (2019). 8 (3): 207. https://pdfs.semanticscholar.org/4ea9/74f0fadb57a0b1ec35cbc5b3eb28e9b966d8.pdf. We applied the Louvain and the Leiden algorithm to exactly the same networks, using the same seed for the random number generator. Based on this partition, an aggregate network is created (c). Good, B. H., De Montjoye, Y. The random component also makes the algorithm more explorative, which might help to find better community structures. Rather than evaluating the modularity gain for moving a node to each neighboring communities, we choose a neighboring node at random and evaluate whether there is a gain in modularity if we were to move the node to that neighbors community. Leiden keeps finding better partitions for empirical networks also after the first 10 iterations of the algorithm. The Louvain algorithm10 is very simple and elegant. The idea of the refinement phase in the Leiden algorithm is to identify a partition \({{\mathscr{P}}}_{{\rm{refined}}}\) that is a refinement of \({\mathscr{P}}\). Nodes 13 should form a community and nodes 46 should form another community. & Fortunato, S. Community detection algorithms: A comparative analysis. Later iterations of the Louvain algorithm only aggravate the problem of disconnected communities, even though the quality function (i.e. The inspiration for this method of community detection is the optimization of modularity as the algorithm progresses. Phys. However, in the case of the Web of Science network, more than 5% of the communities are disconnected in the first iteration. In all experiments reported here, we used a value of 0.01 for the parameter that determines the degree of randomness in the refinement phase of the Leiden algorithm. In other words, communities are guaranteed to be well separated. The authors show that the total computational time for Louvain depends a lot on the number of phase one loops (loops during the first local moving stage). Fast Unfolding of Communities in Large Networks. Journal of Statistical , January. E 74, 016110, https://doi.org/10.1103/PhysRevE.74.016110 (2006). 1 and summarised in pseudo-code in AlgorithmA.1 in SectionA of the Supplementary Information. Natl. For all networks, Leiden identifies substantially better partitions than Louvain. One of the most popular algorithms to optimise modularity is the so-called Louvain algorithm10, named after the location of its authors. In particular, we show that Louvain may identify communities that are internally disconnected. If you cant use Leiden, choosing Smart Local Moving will likely give very similar results, but might be a bit slower as it doesnt include some of the simple speedups to Louvain like random moving and Louvain pruning. By submitting a comment you agree to abide by our Terms and Community Guidelines. Communities in Networks. HiCBin: binning metagenomic contigs and recovering metagenome-assembled They show that the original Louvain algorithm that can result in badly connected communities (even communities that are completely disconnected internally) and propose an alternative method, Leiden, that guarantees that communities are well connected. Eng. ADS A. Speed and quality of the Louvain and the Leiden algorithm for benchmark networks of increasing size (two iterations). Rev. A community is subpartition -dense if it can be partitioned into two parts such that: (1) the two parts are well connected to each other; (2) neither part can be separated from its community; and (3) each part is also subpartition -dense itself. Article The DBLP network is somewhat more challenging, requiring almost 80 iterations on average to reach a stable iteration. To find an optimal grouping of cells into communities, we need some way of evaluating different partitions in the graph. However, as increases, the Leiden algorithm starts to outperform the Louvain algorithm. The Leiden algorithm has been specifically designed to address the problem of badly connected communities. Phys. Moreover, when no more nodes can be moved, the algorithm will aggregate the network. https://doi.org/10.1038/s41598-019-41695-z, DOI: https://doi.org/10.1038/s41598-019-41695-z. It partitions the data space and identifies the sub-spaces using the Apriori principle. Subset optimality is the strongest guarantee that is provided by the Leiden algorithm. You are using a browser version with limited support for CSS. E 78, 046110, https://doi.org/10.1103/PhysRevE.78.046110 (2008). In the worst case, communities may even be disconnected, especially when running the algorithm iteratively. When the Leiden algorithm found that a community could be split into multiple subcommunities, we counted the community as badly connected. USA 104, 36, https://doi.org/10.1073/pnas.0605965104 (2007). However, as shown in this paper, the Louvain algorithm has a major shortcoming: the algorithm yields communities that may be arbitrarily badly connected. Agglomerative clustering is a bottom-up approach. Nature 433, 895900, https://doi.org/10.1038/nature03288 (2005). You signed in with another tab or window. The count of badly connected communities also included disconnected communities. This will compute the Leiden clusters and add them to the Seurat Object Class. A Simple Acceleration Method for the Louvain Algorithm. Int. wrote the manuscript. CAS Empirical networks show a much richer and more complex structure. The Beginner's Guide to Dimensionality Reduction. E 81, 046106, https://doi.org/10.1103/PhysRevE.81.046106 (2010). The difference in computational time is especially pronounced for larger networks, with Leiden being up to 20 times faster than Louvain in empirical networks. In the case of the Louvain algorithm, after a stable iteration, all subsequent iterations will be stable as well. Luecken, M. D. Application of multi-resolution partitioning of interaction networks to the study of complex disease. Article These steps are repeated until the quality cannot be increased further. Louvain keeps visiting all nodes in a network until there are no more node movements that increase the quality function. (We ensured that modularity optimisation for the subnetwork was fully consistent with modularity optimisation for the whole network13) The Leiden algorithm was run until a stable iteration was obtained. Again, if communities are badly connected, this may lead to incorrect inferences of topics, which will affect bibliometric analyses relying on the inferred topics. Additionally, we implemented a Python package, available from https://github.com/vtraag/leidenalg and deposited at Zenodo24). Fortunato, Santo, and Marc Barthlemy. Presumably, many of the badly connected communities in the first iteration of Louvain become disconnected in the second iteration. It states that there are no communities that can be merged. For this network, Leiden requires over 750 iterations on average to reach a stable iteration. In the most difficult case (=0.9), Louvain requires almost 2.5 days, while Leiden needs fewer than 10 minutes. Hence, the Leiden algorithm effectively addresses the problem of badly connected communities. The resolution limit describes a limitation where there is a minimum community size able to be resolved by optimizing modularity (or other related functions). This represents the following graph structure. Phys. Default behaviour is calling cluster_leiden in igraph with Modularity (for undirected graphs) and CPM cost functions. The above results shows that the problem of disconnected and badly connected communities is quite pervasive in practice. Acad. In the meantime, to ensure continued support, we are displaying the site without styles This continues until the queue is empty. One of the best-known methods for community detection is called modularity3. Performance of modularity maximization in practical contexts. In single-cell biology we often use graph-based community detection methods to do this, as these methods are unsupervised, scale well, and usually give good results. The value of the resolution parameter was determined based on the so-called mixing parameter 13. 81 (4 Pt 2): 046114. http://dx.doi.org/10.1103/PhysRevE.81.046114. In the aggregation phase, an aggregate network is created based on the partition obtained in the local moving phase. Ph.D. thesis, (University of Oxford, 2016). The Leiden algorithm consists of three phases: (1) local moving of nodes, (2) refinement of the partition and (3) aggregation of the network based on the refined partition, using the non-refined. Package 'leiden' October 13, 2022 Type Package Title R Implementation of Leiden Clustering Algorithm Version 0.4.3 Date 2022-09-10 Description Implements the 'Python leidenalg' module to be called in R. Enables clustering using the leiden algorithm for partition a graph into communities. For example, after four iterations, the Web UK network has 8% disconnected communities, but twice as many badly connected communities. The R implementation of Leiden can be run directly on the snn igraph object in Seurat. To overcome the problem of arbitrarily badly connected communities, we introduced a new algorithm, which we refer to as the Leiden algorithm. Scanpy Tutorial - 65k PBMCs - Parse Biosciences This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository. We used modularity with a resolution parameter of =1 for the experiments. In addition, to analyse whether a community is badly connected, we ran the Leiden algorithm on the subnetwork consisting of all nodes belonging to the community. Contrary to what might be expected, iterating the Louvain algorithm aggravates the problem of badly connected communities, as we will also see in our experimental analysis. Cluster Determination FindClusters Seurat - Satija Lab Newman, M. E. J. Google Scholar. In addition, we prove that the algorithm converges to an asymptotically stable partition in which all subsets of all communities are locally optimally assigned. Unlike the Louvain algorithm, the Leiden algorithm uses a fast local move procedure in this phase. The Leiden algorithm provides several guarantees. 2013. This contrasts to benchmark networks, for which Leiden often converges after a few iterations. All authors conceived the algorithm and contributed to the source code. Data 11, 130, https://doi.org/10.1145/2992785 (2017). As we will demonstrate in our experimental analysis, the problem occurs frequently in practice when using the Louvain algorithm. Leiden is the most recent major development in this space, and highlighted a flaw in the original Louvain algorithm (Traag, Waltman, and Eck 2018). scanpy.tl.leiden Scanpy 1.9.3 documentation - Read the Docs Four popular community detection algorithms are explained . leiden: Run Leiden clustering algorithm in leiden: R Implementation of A partition of clusters as a vector of integers Examples Moreover, when the algorithm is applied iteratively, it converges to a partition in which all subsets of all communities are guaranteed to be locally optimally assigned. CAS For the Amazon and IMDB networks, the first iteration of the Leiden algorithm is only about 1.6 times faster than the first iteration of the Louvain algorithm. The percentage of badly connected communities is less affected by the number of iterations of the Louvain algorithm. Higher resolutions lead to more communities and lower resolutions lead to fewer communities, similarly to the resolution parameter for modularity. Community detection is often used to understand the structure of large and complex networks. This contrasts with the Leiden algorithm. The Leiden algorithm is typically iterated: the output of one iteration is used as the input for the next iteration. To ensure readability of the paper to the broadest possible audience, we have chosen to relegate all technical details to the Supplementary Information. Phys. Article Phys. However, nodes 16 are still locally optimally assigned, and therefore these nodes will stay in the red community. sign in Modularity scores of +1 mean that all the edges in a community are connecting nodes within the community. Google Scholar. The algorithm then moves individual nodes in the aggregate network (e). leiden clustering explained Each community in this partition becomes a node in the aggregate network. We generated benchmark networks in the following way. First, we show that the Louvain algorithm finds disconnected communities, and more generally, badly connected communities in the empirical networks. Speed and quality for the first 10 iterations of the Louvain and the Leiden algorithm for six empirical networks. When node 0 is moved to a different community, the red community becomes internally disconnected, as shown in (b). Number of iterations until stability. The aggregate network is created based on the partition \({{\mathscr{P}}}_{{\rm{refined}}}\). However, it is also possible to start the algorithm from a different partition15. Ayan Sinha, David F. Gleich & Karthik Ramani, Marinka Zitnik, Rok Sosi & Jure Leskovec, Zhenqi Lu, Johan Wahlstrm & Arye Nehorai, Natalie Stanley, Roland Kwitt, Peter J. Mucha, Scientific Reports The larger the increase in the quality function, the more likely a community is to be selected. We start by initialising a queue with all nodes in the network. As can be seen in the figure, Louvain quickly reaches a state in which it is unable to find better partitions. Note that nodes can be revisited several times within a single iteration of the local moving stage, as the possible increase in modularity will change as other nodes are moved to different communities. Get the most important science stories of the day, free in your inbox. Hence, the community remains disconnected, unless it is merged with another community that happens to act as a bridge. Fortunato, S. Community detection in graphs. Then, in order . We show that this algorithm has a major defect that largely went unnoticed until now: the Louvain algorithm may yield arbitrarily badly connected communities. Consider the partition shown in (a).

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leiden clustering explained